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RCAN1 Antibody
RCAN1 Antibody
产品编?#29275;?/td> 25-434
规  格:
单  价: 询价
生 产 商: ProSci
到货时间: 2-3weeks
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BACKGROUND
RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.

ALTERNATE NAMES
RCAN1, ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1

CONJUGATE
Unconjugated

PURIFICATION
Antibody is purified by peptide affinity chromatography method.

HOST SPECIES
Rabbit

CLONALITY
Polyclonal

ISOTYPE


IMMUNOGEN


TESTED APPLICATIONS
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RCAN1.

APPLICATIONS
E, WB

BUFFER
RCAN1 antibody can be used for detection of RCAN1 by ELISA at 1:312500. RCAN1 antibody can be used for detection of RCAN1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

STORAGE CONDITIONS
For short periods of storage (days) store at 4˚C. For longer periods of storage, store RCAN1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

SPECIES REACTIVITY
Human, Mouse, Rat
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